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Most pathways can be related to the pathogenesis of Alzheimers Disease

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Together, our findings support that TGF 1 is driving BBB permeability via downregulation of claudin-5 and upregulation of MMP9 and that these effects are dependent on SMAD3

Some clients may experience headaches, mild gastrointestinal discomfort, difficulty sleeping, or mood shifts

PMCID: PMC2854129

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